Headline: Amgen Inc. Q4 Profit Surges, Shares Jump - AMGN

[Para 1: The Lead] Amgen Inc. (AMGN) reported a 12% increase in Q4 profit to $4.5 billion, exceeding analyst estimates, boosting its share price by 5% post-earnings. The biotechnology giant's strong performance is attributed to robust sales of its key products and cost savings. [Para 2-3: Supporting details & Context] The company's revenue climbed 8% to $11.2 billion, driven by growth in its cardiovascular and oncology franchises. Earnings per share (EPS) were $13.50, surpassing the consensus estimate of $12.10. Amgen's cost-saving measures, including operational efficiencies, contributed to the improved financial results. Analysts are optimistic about the company's future prospects, citing continued innovation and market leadership.