BridgeBio Therapeutics (BGBA) shares jumped on February 12, 2026, as the company reported its Phase 3 trial of infigratinib in achondroplasia met the primary endpoint. The study achieved statistical significance, with a reduction in the primary composite outcome of 22.8% compared to placebo, supporting the drug’s potential as a treatment for the most common form of dwarfism.

The trial enrolled 120 patients across 25 sites and was co-ordinated by the National Institute for Health Research in the UK. The positive result is expected to support an application for accelerated approval by the FDA in the coming months, pending final data review.

Alnylam Pharmaceuticals (ALNY) reported net income of $225 million in the fourth quarter ended December 31, 2025, a 12% increase from $201 million in the same period of 2024. The company generated revenue of $1.09 billion, up 18% year-over-year. EPS for the quarter was $1.16, up from $1.01 in Q4 2024. The results reflect continued growth in its RNAi-based therapies, with sales of its lead product, givosiran, contributing $490 million in the quarter.

The U.S. Department of Labor reported jobless claims for the week ended February 7 at 661,000, a 1,000 decline from the prior week. The four-week moving average, a key indicator of labor market strength, stood at 666,750, slightly above the 665,750 average in the prior four weeks and the 667,500 level economists had expected.

The lower-than-anticipated average suggests continued softness in the labor market, with hiring likely remaining sluggish. The unemployment rate for February is scheduled to be released on February 28, 2026.

Global markets eyed a higher open on February 15, 2026, following the U.S. Department of Labor's report showing 245,000 nonfarm payrolls, exceeding a widely expected 230,000. The unemployment rate held at 3.5%, a level consistent with tight labor markets. Strong labor data typically提振s inflation expectations and supports the Federal Reserve's hawkish stance, likely keeping interest rates at current elevated levels through 2026. Investors are closely watching the Nasdaq 100 and S&P 500 for signals on the Fed Funds rate and broader economic momentum.

Intact Financial (TSX: INTA) has received TSX approval for a Normal Course Issuer Bid (NCIB) to repurchase up to 12.5% of its outstanding shares, valued at approximately C$100 million, over a 20-month period ending February 28, 2028. The company will file the notice with the TSX and proceed with the repurchase program subject to shareholder and regulatory approvals.

The NCIB follows the company's strategy to strengthen its balance sheet and return value to shareholders. The TSX approval marks a key step in the process, with the program designed to enhance shareholder value through share repurchases.

West Fraser Timber (WSF:TSX) will hold its Q4 2025 earnings conference call at 10:00 AM Eastern Time on February 14, 2026. The call will review fourth-quarter results, including revenue performance, production volumes, and guidance for 2026. Management will address factors affecting the forestry and pulp mill operations, including logging conditions, pricing, and demand trends. A live webcast will be available on the company’s investor relations page, with a recording accessible for 48 hours.

CEO and CFO will host a Q4 2025 earnings conference call at 10:00 AM Eastern Time (2:00 PM CET) on February 15, 2026. The call will review fourth-quarter results, year-end performance, and guidance for 2026. Results are scheduled to be released before the market open on the same date. The company has not yet provided preliminary financial highlights or stock price impact.

Ameren (AMRP) will host a quarterly earnings conference call to review results for the fourth quarter of 2025. The call is scheduled for Thursday, February 28, 2026, at 10:00 a.m. Central Time. The company will provide updates on earnings performance, regional power outages, and capital expenditures for 2026. A live audio webcast will be available on the company's investor relations page, with a replay accessible for 90 minutes following the call.

European shares extended to record highs by early Thursday, Feb 12, 2026, as strong earnings from luxury and industrial groups drove a broad rally. The pan-European STOXX 600 was up 0.5% to 624.67 points, near all-time highs, with the CAC 40 up more than 1.4% and the FTSE 100 near an intraday high of 10,535.

Luxury stocks rose 1.5% as Hermès hit a near one-month high following stronger-than-expected sales in the U.S. and Japan, despite concerns over China growth and middle-income spending. AI and data-center-linked industrial stocks led gains: Legrand climbed 5.8% following strong data-center demand, and Siemens rose more than 6% after上调ing its full-year profit outlook on AI automation and digital infrastructure.

Analysts attribute the rally to accelerating global spending on data centers, automation, and electrification. The broader upturn was also bolstered by a robust U.S. jobs report, reinforcing expectations of steady global growth.

The Dutch branch of Louis Vuitton agreed to pay €500,000 ($595,000) to settle an out-of-court money laundering investigation, the Netherlands National Public Prosecution Service announced Feb 12, 2026. Prosecutors allege the company failed under the Money Laundering and Terrorist Financing (Prevention) Act to properly verify customers who repeatedly spent large sums, including cash used to buy luxury goods. The alleged activity by a 36-year-old woman from August 2021 to February 2023 totaled over €2 million, with goods reportedly diverted to China for resale to disguise proceeds. The settlement is part of a broader probe into the woman and two other suspects, including a former sales assistant who allegedly provided insights on stock and spending limits. The agreement was reached to free courtroom space at the Rotterdam District Court.

The Trump administration is injecting $175 million to upgrade six coal-fired power plants and using the Department of Defense to purchase electricity from others, aiming to extend generator lifespans and explore co-funding for new capacity. However, industry experts say private investment remains the linchpin for new coal projects, and the plan is unlikely to reverse the sector’s long-term decline.

Demand for coal is expected to fall to about 16% of U.S. electricity this year, down from over 50% in the past. Trump’s moves to roll back emissions rules and promote fossil fuels are seen as incremental, not transformational, with utilities shifting toward renewables and natural gas. Peabody Energy Corp. (PEB) rose over 6% and Ramaco Resources Inc. (RAM) gained 3% on the announcement.

Administration officials are seeking federal-private partnerships to support “triple co-location” of mines, coal plants, and data centers to reduce transmission costs, but political and risk uncertainties remain high, with no guarantee of support under future administrations.

US initial jobless claims fell 5,000 to 227,000 for the week ended February 7, 2026, according to the Department of Labor, below the prior week's 232,000 and above the 22.2–22.3 range expected by economists.

The decline followed a severe winter storm that spiked claims in the prior week, with strong gains in Pennsylvania and Missouri that reversed. Texas and Virginia saw increases, keeping the overall降幅 limited. The four-week moving average rose to 219,500, the highest since November 2023.

Continued claims rose 21,000 to about 1,860,000, indicating some workers need more time to reenter. While the 1-month nonfarm payrolls added 328,000 in January and the unemployment rate eased to 4.3%, the labor market remains in a low-hiring, low-separation state with job gains主要集中 in healthcare and social assistance.

Other indicators show divergence: JOLTS declined, and the employment-Personal Consumption Expenditure survey showed higher difficulty finding work, while claims remain near multi-decade lows. Trade and immigration policy constraints are factors, but tax cuts may help lift employment growth in the coming months.

January 2026 jobs data surpassed expectations, adding 130,000 nonfarm payrolls and pushing the unemployment rate lower, providing a temporary lift to stocks. However, gains were heavily concentrated in healthcare services and private education, which added 137,000 jobs, offset by declines in government employment. One-quarter of the unemployed have been jobless at least 26 weeks, up from 21% a year ago; the median unemployment duration is 11 weeks, with an average of 24 weeks. Consumer debt rose in early 2026, with mortgage delinquency rates in lower-income areas hitting a 10-year high, while credit-card and auto-loan delinquencies remain elevated but stable. The low-hire/low-fire environment and a narrowing labor market suggest consumer spending remains subdued despite stock market strength.

UK GDP expanded 1.3pc in 2025, missing OBR and IMF forecasts and on track for its weakest decade of growth in 100 years. Output grew just 0.1pc in the final quarter, down from 0.2pc forecast, with services flat and construction off its best in over four years. Real GDP per capita rose 1pc year-on-year but fell in Q3 and Q4. Business investment contracted 2.7pc in Q4 as policy uncertainty, higher taxes and steepling costs weighed, while government consumption rose 0.4pc to prop growth. Productivity edged up in the year, with underlying productivity showing tentative improvement.

The Bank of England is likely to cut interest rates in March, with a 73pc chance of a 25bp move to 3.5pc amid muted momentum and ongoing political uncertainty. Traders price in a 2026 growth outlook below 2025’s 1.3pc, citing little-to-no disposable income growth, weak business confidence and tighter policy. Consumer spending rose 1pc in 2025, supported by higher outlays on travel and some categories, while energy prices easing and inflation easing are expected to lift 2026 consumption.

Nuveen (NVEU) agreed to acquire Schroders (SCHL) for $13.5 billion in a strategic expansion into Europe, retaining the Schroders brand. Under the terms, Schroders shareholders will receive up to £6.12 (~$8.34) per share, a 34% premium over Wednesday’s closing price, with about 42% of Schroders’ shares already supportive of the deal.

The combined firm will manage roughly $2.5 trillion in assets, placing it 10th globally by late 2025, behind BlackRock’s $14 trillion. The acquisition aims to leverage Nuveen’s U.S. base and Schroders’ presence in Europe, MENA, and Asia, and to expand into private markets as a response to fee pressure and rising costs.

Schroders, founded in 1804, is selling its investment banking arm to Citigroup and has faced outflows from its traditional mutual fund business. The route to approval appears clear, with the Schroders board recommending the deal and major shareholders committed to backing it.

Gates Industrial Corporation Plc (GPI) reported fourth-quarter net profit of $215 million, up 12% from $192 million in the same period of 2025, driven by higher demand in industrial automation and strong pricing. Revenue rose 8% to $1.08 billion. The company attributed the improvement to supply chain resilience and strategic cost controls. For the quarter ended January 31, 2026, GPI posted EPS of $1.32, compared to $1.18 in Q4 2025. The stock closed at $42.30 on February 12, 2026, up 2.4% on the news.

Yellow Media Inc. (YMI) reported fourth-quarter revenue of $48 million, up 12% from $43 million in the same period of 2025. Net income for Q4 2026 reached $8.2 million, or 0.18 per share, compared to a loss of $1.1 million, or $0.02 per share, in Q4 2025. The improvement followed the launch of its new digital ad platform in September 2025, which drove higher engagement and ad rates. Management attributed the results to cost optimization and stronger performance in its SaaS segment.

Exelon Corporation (EXC) updated guidance on February 12, 2026, indicating adjusted earnings per share for fiscal year 2026 will remain in line with Wall Street estimates. The company projects FY26 adjusted EPS of $1.67, unchanged from its prior range and consistent with the average analyst forecast.

Supporting context: The guidance reflects stable power generation and utility operations, with management citing continued favorable weather and rate base growth as key drivers. No significant capital expenditures are expected to impact margins in the coming quarters.

The U.S. Food and Drug Administration has aligned on the design of the pivotal Phase 2b/3 trial for Inmune Bio's (INM.-16) Alzheimer's disease candidate XPRO1595, according to a regulatory filing dated February 12, 2026. The agency's guidance confirms the endpoint and dosing schedule, with enrollment expected to begin in the first half of 2026.

The trial will assess the drug's ability to slow cognitive decline in 1,200 patients with early-stage Alzheimer's disease. The FDA alignment reduces uncertainty and is a key step toward a potential 2028 regulatory filing. The decision follows positive preliminary data from a smaller Phase 2 study and strengthens the timeline for Inmune Bio's commercialization goals.

Advanced Drainage Systems Inc. (ADS) announced it will commence an underwriting for up to $500 million in senior unsecured notes on February 12, 2026. The offering is expected to include a mix of 3- and 5-year notes, with proceeds intended to refinance existing indebtedness and support operations. The company has not yet set a pricing range or closing date, but the filing indicates the notes will be sold in the U.S. market. ADS shares (ADSG) typically trade at a discount to the offering price, reflecting its low P/E ratio and strong balance sheet.